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 Though all pimples                           start the same way, they can take many forms and may                           react differently for different people. Please note that                           the following guide is not intended to be used for                           conclusive self-diagnosis. These definitions may be used                           to help you decide whether or not you should consider                           seeking medical attention.
 
 Closed comedo,                           or whitehead.
 If the plugged follicle stays below                           the surface of the skin, the lesion is called a closed                           comedo, or whitehead. They usually appear on the skin as                           small, whitish bumps.
 
 Open comedo, or                           blackhead.
 If the plug enlarges and pushes through                           the surface of the skin,                           it's called an open comedo, or blackhead. The plug's                           dark appearance is not due to dirt, but rather to a                           buildup of melanin, the skin's dark pigment.
 
 Papule.
 The mildest form of inflammatory                           acne is the papule, which appears on the skin as a                           small, firm pink bump. These can be tender to the touch,                           and are often considered an intermediary step between                           non-inflammatory and clearly inflammatory                           lesions.
 
 Pustule.
 Like papules,                           pustules are small round lesions; unlike papules, they                           are clearly inflamed                           and contain visible pus. They may appear red at the                           base, with a yellowish or whitish center. Pustules do                           not commonly contain a great deal of bacteria; the                           inflammation is generally caused by chemical irritation                           from sebum components such as fatty free                           acids.
 
 Nodule or Cyst.
 Large and                           usually very painful,                           nodules are inflamed, pus-filled lesions lodged deep                           within the skin. Nodules develop when the contents of a                           comedo have spilled into the surrounding skin and the                           local immune system responds, producing pus. The most                           severe form of acne lesion, nodules may persist for                           weeks or months, their contents hardening into a deep                           cyst. Both nodules and cysts often leave deep                           scars.
 
 Acne conglobata.
 This rare but                           serious form of inflammatory acne develops primarily on                           the back, buttocks and chest. In addition to the                           presence of pustules and nodules, there may be severe                           bacterial infection.
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